Impact of Pseudomonas aeruginosa quorum sensing signaling molecules on adhesion and inflammatory markers in endothelial cells

• Carmen Curutiu,
• Florin Iordache,
• Veronica Lazar,
• Aurelia Magdalena Pisoschi,
• Aneta Pop,
• Mariana Carmen Chifiriuc and
• Alina Maria Hoban

Beilstein J. Org. Chem. 2018, 14, 2580–2588, doi:10.3762/bjoc.14.235

• develop anti-QS therapeutic strategies to fight against P. aeruginosa infections. Keywords: adhesion; host–pathogen interaction; inflammation; Pseudomonas; quorum sensing; Introduction Pseudomonas (P.) aeruginosa is an opportunistic pathogen that causes severe and persistent infections in immune

• help in gaining insights into understanding host–pathogen interaction and communication and may have an impact on the development of new anti-QS therapeutic strategies to fight P. aeruginosa infections. Specifically, our results bring new information to help elucidating the mechanisms by which

Glyco-gold nanoparticles: synthesis and applications

• Federica Compostella,
• Olimpia Pitirollo,
• Alessandro Silvestri and
• Laura Polito

Beilstein J. Org. Chem. 2017, 13, 1008–1021, doi:10.3762/bjoc.13.100

• Galf, a five-membered form of galactose found in nonmammalian pathogenic species, i.e., the fungus Aspergillus, is able to modulate the innate immune response via dendritic cells, suggesting Galf-GNPs as versatile tools in functional studies to address the role of Galf in host-pathogen interaction. DC